Science 28 October 1988: Vol. 242. no. 4878, pp. 540 - 546 DOI: 10.1126/science.3140380

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Articles

Oxidized Hemoglobin Is an Endogenous Proinflammatory Agonist That Targets Vascular Endothelial Cells.

G. Silva, V. Jeney, A. Chora, R. Larsen, J. Balla, and M. P. Soares (2009)
J. Biol. Chem. 284, 29582-29595
 |  Abstract »  |  Full Text »  |  PDF »

Specification of DNA Binding Activity of NF-{kappa}B Proteins.

F. Wan and M. J. Lenardo (2009)
Cold Spring Harb Perspect Biol 1, a000067
 |  Abstract »  |  Full Text »  |  PDF »

Gene Transfer of Inducible Nitric Oxide Synthase Affords Cardioprotection by Upregulating Heme Oxygenase-1 Via a Nuclear Factor-{kappa}B-Dependent Pathway.

Q. Li, Y. Guo, Q. Ou, C. Cui, W.-J. Wu, W. Tan, X. Zhu, L. B. Lanceta, S. K. Sanganalmath, B. Dawn, et al. (2009)
Circulation 120, 1222-1230
 |  Abstract »  |  Full Text »  |  PDF »

CD14 and Toll-Like Receptors 2 and 4 Are Required for Fibrillar A{beta}-Stimulated Microglial Activation.

E. G. Reed-Geaghan, J. C. Savage, A. G. Hise, and G. E. Landreth (2009)
J. Neurosci. 29, 11982-11992
 |  Abstract »  |  Full Text »  |  PDF »

Probiotic Lactobacillus casei strain Shirota prevents indomethacin-induced small intestinal injury: involvement of lactic acid.

T. Watanabe, H. Nishio, T. Tanigawa, H. Yamagami, H. Okazaki, K. Watanabe, K. Tominaga, Y. Fujiwara, N. Oshitani, T. Asahara, et al. (2009)
Am J Physiol Gastrointest Liver Physiol 297, G506-G513
 |  Abstract »  |  Full Text »  |  PDF »

Targeting NF-{kappa}B signaling pathway suppresses tumor growth, angiogenesis, and metastasis of human esophageal cancer.

B. Li, Y. Y. Li, S. W. Tsao, and A. L.M. Cheung (2009)
Mol. Cancer Ther. 8, 2635-2644
 |  Abstract »  |  Full Text »  |  PDF »

A Structural Guide to Proteins of the NF-{kappa}B Signaling Module.

T. Huxford and G. Ghosh (2009)
Cold Spring Harb Perspect Biol 1, a000075
 |  Abstract »  |  Full Text »  |  PDF »

Discovering NF-{kappa}B.

D. Baltimore (2009)
Cold Spring Harb Perspect Biol 1, a000026
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Suppression of LPS-Induced TNF-{alpha} Production in Macrophages by cAMP Is Mediated by PKA-AKAP95-p105.

E. A. Wall, J. R. Zavzavadjian, M. S. Chang, B. Randhawa, X. Zhu, R. C. Hsueh, J. Liu, A. Driver, X. R. Bao, P. C. Sternweis, et al. (2009)
Science Signaling 2, ra28
 |  Abstract »  |  Full Text »  |  PDF »

Kinetic control of negative feedback regulators of NF-{kappa}B/RelA determines their pathogen- and cytokine-receptor signaling specificity.

V. F.-S. Shih, J. D. Kearns, S. Basak, O. V. Savinova, G. Ghosh, and A. Hoffmann (2009)
PNAS 106, 9619-9624
 |  Abstract »  |  Full Text »  |  PDF »

GCN5 is a required cofactor for a ubiquitin ligase that targets NF-{kappa}B/RelA.

X. Mao, N. Gluck, D. Li, G. N. Maine, H. Li, I. W. Zaidi, A. Repaka, M. W. Mayo, and E. Burstein (2009)
Genes & Dev. 23, 849-861
 |  Abstract »  |  Full Text »  |  PDF »

New Mechanism of Rosiglitazone to Reduce Neointimal Hyperplasia: Activation of Glycogen Synthase Kinase-3{beta} Followed by Inhibition of MMP-9.

C.-S. Lee, Y.-W. Kwon, H.-M. Yang, S.-H. Kim, T.-Y. Kim, J. Hur, K.-W. Park, H.-J. Cho, H.-J. Kang, Y.-B. Park, et al. (2009)
Arterioscler Thromb Vasc Biol 29, 472-479
 |  Abstract »  |  Full Text »  |  PDF »

Synergistic Induction of Inflammation by Bacterial Products Lipopolysaccharide and fMLP: An Important Microbial Pathogenic Mechanism.

L.-Y. Chen, W. W. Pan, M. Chen, J.-D. Li, W. Liu, G. Chen, S. Huang, T. J. Papadimos, and Z. K. Pan (2009)
J. Immunol. 182, 2518-2524
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-1 Regulates the Expression of Sphingosine Kinase 1 in Glioblastoma Cells.

B. S. Paugh, L. Bryan, S. W. Paugh, K. M. Wilczynska, S. M. Alvarez, S. K. Singh, D. Kapitonov, H. Rokita, S. Wright, I. Griswold-Prenner, et al. (2009)
J. Biol. Chem. 284, 3408-3417
 |  Abstract »  |  Full Text »  |  PDF »

Diarctigenin, a Lignan Constituent from Arctium lappa, Down-Regulated Zymosan-Induced Transcription of Inflammatory Genes through Suppression of DNA Binding Ability of Nuclear Factor-{kappa}B in Macrophages.

B. H. Kim, S. S. Hong, S. W. Kwon, H. Y. Lee, H. Sung, I.-J. Lee, B. Y. Hwang, S. Song, C.-K. Lee, D. Chung, et al. (2008)
J. Pharmacol. Exp. Ther. 327, 393-401
 |  Abstract »  |  Full Text »  |  PDF »

Forkhead Transcription Factors (FoxOs) Promote Apoptosis of Insulin-Resistant Macrophages During Cholesterol-Induced Endoplasmic Reticulum Stress.

T. Senokuchi, C.-P. Liang, T. A. Seimon, S. Han, M. Matsumoto, A. S. Banks, J.-H. Paik, R. A. DePinho, D. Accili, I. Tabas, et al. (2008)
Diabetes 57, 2967-2976
 |  Abstract »  |  Full Text »  |  PDF »

Hydrogen Peroxide Prolongs Nuclear Localization of NF-{kappa}B in Activated Cells by Suppressing Negative Regulatory Mechanisms.

K. Enesa, K. Ito, L. A. Luong, I. Thorbjornsen, C. Phua, Y. To, J. Dean, D. O. Haskard, J. Boyle, I. Adcock, et al. (2008)
J. Biol. Chem. 283, 18582-18590
 |  Abstract »  |  Full Text »  |  PDF »

Depletion of {beta}-Arrestin-2 Promotes Tumor Growth and Angiogenesis in a Murine Model of Lung Cancer.

S. K. Raghuwanshi, M. W. Nasser, X. Chen, R. M. Strieter, and R. M. Richardson (2008)
J. Immunol. 180, 5699-5706
 |  Abstract »  |  Full Text »  |  PDF »

Benzoxathiole Derivative Blocks Lipopolysaccharide-Induced Nuclear Factor-{kappa}B Activation and Nuclear Factor-{kappa}B-Regulated Gene Transcription through Inactivating Inhibitory {kappa}B Kinase {beta}.

B. H. Kim, E. Roh, H. Y. Lee, I.-J. Lee, B. Ahn, S.-H. Jung, H. Lee, S.-B. Han, and Y. Kim (2008)
Mol. Pharmacol. 73, 1309-1318
 |  Abstract »  |  Full Text »  |  PDF »

GPR30 Contributes to Estrogen-Induced Thymic Atrophy.

C. Wang, B. Dehghani, I. J. Magrisso, E. A. Rick, E. Bonhomme, D. B. Cody, L. A. Elenich, S. Subramanian, S. J. Murphy, M. J. Kelly, et al. (2008)
Mol. Endocrinol. 22, 636-648
 |  Abstract »  |  Full Text »  |  PDF »

Transglutaminase Type II Is Involved in the Pathogenesis of Endotoxic Shock.

L. Falasca, M. G. Farrace, A. Rinaldi, L. Tuosto, G. Melino, and M. Piacentini (2008)
J. Immunol. 180, 2616-2624
 |  Abstract »  |  Full Text »  |  PDF »

EGF regulates plasminogen activator inhibitor-1 (PAI-1) by a pathway involving c-Src, PKC{delta}, and sphingosine kinase 1 in glioblastoma cells.

B. S. Paugh, S. W. Paugh, L. Bryan, D. Kapitonov, K. M. Wilczynska, S. M. Gopalan, H. Rokita, S. Milstien, S. Spiegel, and T. Kordula (2008)
FASEB J 22, 455-465
 |  Abstract »  |  Full Text »  |  PDF »

Hormonal control of the renal immune response and antibacterial host defense by arginine vasopressin.

C. Chassin, M. W. Hornef, M. Bens, M. Lotz, J.-M. Goujon, S. Vimont, G. Arlet, A. Hertig, E. Rondeau, and A. Vandewalle (2007)
J. Exp. Med. 204, 2837-2852
 |  Abstract »  |  Full Text »  |  PDF »

Torque Teno Virus (SANBAN Isolate) ORF2 Protein Suppresses NF-{kappa}B Pathways via Interaction with I{kappa}B Kinases.

H. Zheng, L. Ye, X. Fang, B. Li, Y. Wang, X. Xiang, L. Kong, W. Wang, Y. Zeng, L. Ye, et al. (2007)
J. Virol. 81, 11917-11924
 |  Abstract »  |  Full Text »  |  PDF »

Id-1 activation of PI3K/Akt/NF{kappa}B signaling pathway and its significance in promoting survival of esophageal cancer cells.

B. Li, P. Y. Cheung, X. Wang, S. W. Tsao, M. T. Ling, Y. C. Wong, and A. L.M. Cheung (2007)
Carcinogenesis 28, 2313-2320
 |  Abstract »  |  Full Text »  |  PDF »

Elevated NF-{kappa}B responses and FLIP levels in leukemic but not normal lymphocytes: reduction by salicylate allows TNF-induced apoptosis.

C. Rae, S. Langa, S. J. Tucker, and D. J. MacEwan (2007)
PNAS 104, 12790-12795
 |  Abstract »  |  Full Text »  |  PDF »

The Induction of Growth Arrest DNA Damage-Inducible Gene 45 {beta} in Human Hepatoma Cell Lines by S-Adenosylmethionine.

W. Qiu, B. Zhou, P. G. Chu, F. Luh, and Y. Yen (2007)
Am. J. Pathol. 171, 287-296
 |  Abstract »  |  Full Text »  |  PDF »

Atiprimod inhibits the growth of mantle cell lymphoma in vitro and in vivo and induces apoptosis via activating the mitochondrial pathways.

M. Wang, L. Zhang, X. Han, J. Yang, J. Qian, S. Hong, F. Samaniego, J. Romaguera, and Q. Yi (2007)
Blood 109, 5455-5462
 |  Abstract »  |  Full Text »  |  PDF »

Hydrogen sulfide induces the synthesis of proinflammatory cytokines in human monocyte cell line U937 via the ERK-NF-{kappa}B pathway.

L. Zhi, A. D. Ang, H. Zhang, P. K. Moore, and M. Bhatia (2007)
J. Leukoc. Biol. 81, 1322-1332
 |  Abstract »  |  Full Text »  |  PDF »

The differential expression of corticosteroid receptor isoforms in corticosteroid-resistant and -sensitive patients with rheumatoid arthritis.

D. L. Kozaci, Y. Chernajovsky, and I. C. Chikanza (2007)
Rheumatology 46, 579-585
 |  Abstract »  |  Full Text »  |  PDF »

A Transgenic Model Reveals Important Roles for the NF-{kappa}B Alternative Pathway (p100/p52) in Mammary Development and Links to Tumorigenesis.

L. Connelly, C. Robinson-Benion, M. Chont, L. Saint-Jean, H. Li, V. V. Polosukhin, T. S. Blackwell, and F. E. Yull (2007)
J. Biol. Chem. 282, 10028-10035
 |  Abstract »  |  Full Text »  |  PDF »

Keratinocyte Growth Factor/Fibroblast Growth Factor-7-regulated Cell Migration and Invasion through Activation of NF-{kappa}B Transcription Factors.

J. Niu, Z. Chang, B. Peng, Q. Xia, W. Lu, P. Huang, M.-S. Tsao, and P. J. Chiao (2007)
J. Biol. Chem. 282, 6001-6011
 |  Abstract »  |  Full Text »  |  PDF »

Novel Genomic Effects of Glucocorticoids in Epidermal Keratinocytes: INHIBITION OF APOPTOSIS, INTERFERON-{gamma} PATHWAY, AND WOUND HEALING ALONG WITH PROMOTION OF TERMINAL DIFFERENTIATION.

O. Stojadinovic, B. Lee, C. Vouthounis, S. Vukelic, I. Pastar, M. Blumenberg, H. Brem, and M. Tomic-Canic (2007)
J. Biol. Chem. 282, 4021-4034
 |  Abstract »  |  Full Text »  |  PDF »

I{kappa}B Kinase Subunits {alpha} and {gamma} Are Required for Activation of NF-{kappa}B and Induction of Apoptosis by Mammalian Reovirus.

M. W. Hansberger, J. A. Campbell, P. Danthi, P. Arrate, K. N. Pennington, K. B. Marcu, D. W. Ballard, and T. S. Dermody (2007)
J. Virol. 81, 1360-1371
 |  Abstract »  |  Full Text »  |  PDF »

Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NF{kappa}B.

H.-C. Lee and S. F. Ziegler (2007)
PNAS 104, 914-919
 |  Abstract »  |  Full Text »  |  PDF »

Regions of I{kappa}B{alpha} that are critical for its inhibition of NF-{kappa}B{middle dot}DNA interaction fold upon binding to NF-{kappa}B.

S. M. E. Truhlar, J. W. Torpey, and E. A. Komives (2006)
PNAS 103, 18951-18956
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Mechanism of Tissue Inhibitor of Metalloproteinases-1 Activation by Interleukin-1 in Primary Human Astrocytes.

K. M. Wilczynska, S. M. Gopalan, M. Bugno, A. Kasza, B. S. Konik, L. Bryan, S. Wright, I. Griswold-Prenner, and T. Kordula (2006)
J. Biol. Chem. 281, 34955-34964
 |  Abstract »  |  Full Text »  |  PDF »

Renal Collecting Duct Epithelial Cells React to Pyelonephritis-Associated Escherichia coli by Activating Distinct TLR4-Dependent and -Independent Inflammatory Pathways.

C. Chassin, J.-M. Goujon, S. Darche, L. du Merle, M. Bens, F. Cluzeaud, C. Werts, E. Ogier-Denis, C. Le Bouguenec, D. Buzoni-Gatel, et al. (2006)
J. Immunol. 177, 4773-4784
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-1-induced NF-{kappa}B recruitment to the oxytocin receptor gene inhibits RNA polymerase II-promoter interactions in cultured human myometrial cells.

M. S. Soloff, M. G. Izban, D. L. Cook Jr, Y.-J. Jeng, and R. C. Mifflin (2006)
Mol. Hum. Reprod. 12, 619-624
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of Tissue Transglutaminase Leads to Constitutive Activation of Nuclear Factor-{kappa}B in Cancer Cells: Delineation of a Novel Pathway..

A. P. Mann, A. Verma, G. Sethi, B. Manavathi, H. Wang, J. Y. Fok, A. B. Kunnumakkara, R. Kumar, B. B. Aggarwal, and K. Mehta (2006)
Cancer Res. 66, 8788-8795
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the Nuclear Factor-{kappa}B Responsiveness of the Human dio2 Gene.

A. Zeold, M. Doleschall, M. C. Haffner, L. P. Capelo, J. Menyhert, Z. Liposits, W. S. da Silva, A. C. Bianco, I. Kacskovics, C. Fekete, et al. (2006)
Endocrinology 147, 4419-4429
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Factor-1-X Regulates Astrocyte-specific Expression of the {alpha}1-Antichymotrypsin and Glial Fibrillary Acidic Protein Genes.

S. M. Gopalan, K. M. Wilczynska, B. S. Konik, L. Bryan, and T. Kordula (2006)
J. Biol. Chem. 281, 13126-13133
 |  Abstract »  |  Full Text »  |  PDF »

Persistent Interleukin-1beta Signaling Causes Long Term Activation of NF{kappa}B in a Promoter-specific Manner in Human Glial Cells.

B. D. Griffin and P. N. Moynagh (2006)
J. Biol. Chem. 281, 10316-10326
 |  Abstract »  |  Full Text »  |  PDF »

3H-1,2-Dithiole-3-thione Targets Nuclear Factor {kappa}B to Block Expression of Inducible Nitric-Oxide Synthase, Prevents Hypotension, and Improves Survival in Endotoxemic Rats.

A. R. Karuri, Y. Huang, S. Bodreddigari, C. H. Sutter, B. D. Roebuck, T. W. Kensler, and T. R. Sutter (2006)
J. Pharmacol. Exp. Ther. 317, 61-67
 |  Abstract »  |  Full Text »  |  PDF »

A Molecular Mechanism for the Anti-Inflammatory Effect of Taurine-Conjugated 5-Aminosalicylic Acid in Inflamed Colon.

H. Kim, H. Jeon, H. Kong, Y. Yang, B. Choi, Y. M. Kim, L. Neckers, and Y. Jung (2006)
Mol. Pharmacol. 69, 1405-1412
 |  Abstract »  |  Full Text »  |  PDF »

Sustained Activation of Phosphatidylinositol 3-Kinase/Akt/Nuclear Factor {kappa}B Signaling Mediates G Protein-coupled {delta}-Opioid Receptor Gene Expression.

Y. L. Chen, P.-Y. Law, and H. H. Loh (2006)
J. Biol. Chem. 281, 3067-3074
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Human Immunodeficiency Virus Type 1 Replication in Latently Infected Cells by a Novel I{kappa}B Kinase Inhibitor.

A. F. B. Victoriano, K. Asamitsu, Y. Hibi, K. Imai, N. G. Barzaga, and T. Okamoto (2006)
Antimicrob. Agents Chemother. 50, 547-555
 |  Abstract »  |  Full Text »  |  PDF »

Astrocyte-specific Expression of the {alpha}1-Antichymotrypsin and Glial Fibrillary Acidic Protein Genes Requires Activator Protein-1.

S. M. Gopalan, K. M. Wilczynska, B. S. Konik, L. Bryan, and T. Kordula (2006)
J. Biol. Chem. 281, 1956-1963
 |  Abstract »  |  Full Text »  |  PDF »

Escherichia coli K1 inhibits proinflammatory cytokine induction in monocytes by preventing NF-{kappa}B activation.

S. K. Selvaraj and N. V. Prasadarao (2005)
J. Leukoc. Biol. 78, 544-554
 |  Abstract »  |  Full Text »  |  PDF »

Breast Cancer Metastasis Suppressor 1 Inhibits Gene Expression by Targeting Nuclear Factor-{kappa}B Activity.

M. Cicek, R. Fukuyama, D. R. Welch, N. Sizemore, and G. Casey (2005)
Cancer Res. 65, 3586-3595
 |  Abstract »  |  Full Text »  |  PDF »

Role Played by Hypothalamic Nuclear Factor-{kappa}B in Alcohol-Mediated Activation of the Rat Hypothalamic-Pituitary-Adrenal Axis.

S. Lee and C. Rivier (2005)
Endocrinology 146, 2006-2014
 |  Abstract »  |  Full Text »  |  PDF »

Requirement of Thyrotropin-Dependent Complex Formation of Protein Kinase A Catalytic Subunit with Inhibitor of {kappa}B Proteins for Activation of p65 Nuclear Factor-{kappa}B by Tumor Necrosis Factor-{alpha}.

X. Cao, F. Kambe, and H. Seo (2005)
Endocrinology 146, 1999-2005
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Factor-{kappa}B Decoys Suppress Endotoxin-Induced Lung Injury.

D. Baetz, J. Shaw, and L. A. Kirshenbaum (2005)
Mol. Pharmacol. 67, 977-979
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Ethyl Pyruvate Inhibits Nuclear Factor-{kappa}B-Dependent Signaling by Directly Targeting p65.

Y. Han, J. A. Englert, R. Yang, R. L. Delude, and M. P. Fink (2005)
J. Pharmacol. Exp. Ther. 312, 1097-1105
 |  Abstract »  |  Full Text »  |  PDF »

Antiapoptotic Effect of Serum and Glucocorticoid-Inducible Protein Kinase Is Mediated by Novel Mechanism Activating I{kappa}B Kinase.

L. Zhang, R. Cui, X. Cheng, and J. Du (2005)
Cancer Res. 65, 457-464
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Factor-{kappa}B Represses Hypoxia-Induced Mitochondrial Defects and Cell Death of Ventricular Myocytes.

K. M. Regula, D. Baetz, and L. A. Kirshenbaum (2004)
Circulation 110, 3795-3802
 |  Abstract »  |  Full Text »  |  PDF »

T-cell Activation Leads to Poor Activation of the HIV-1 Clade E Long Terminal Repeat and Weak Association of Nuclear Factor-{kappa}B and NFAT with Its Enhancer Region.

A.-M. Lemieux, M.-E. Pare, B. Audet, E. Legault, S. Lefort, N. Boucher, S. Landry, T. van Opijnen, B. Berkhout, M. H. Naghavi, et al. (2004)
J. Biol. Chem. 279, 52949-52960
 |  Abstract »  |  Full Text »  |  PDF »

Translational Repression Mediates Activation of Nuclear Factor Kappa B by Phosphorylated Translation Initiation Factor 2.

J. Deng, P. D. Lu, Y. Zhang, D. Scheuner, R. J. Kaufman, N. Sonenberg, H. P. Harding, and D. Ron (2004)
Mol. Cell. Biol. 24, 10161-10168
 |  Abstract »  |  Full Text »  |  PDF »

Vascular Endothelial Growth Factor- and Thrombin-induced Termination Factor, Down Syndrome Critical Region-1, Attenuates Endothelial Cell Proliferation and Angiogenesis.

T. Minami, K. Horiuchi, M. Miura, Md. R. Abid, W. Takabe, N. Noguchi, T. Kohro, X. Ge, H. Aburatani, T. Hamakubo, et al. (2004)
J. Biol. Chem. 279, 50537-50554
 |  Abstract »  |  Full Text »  |  PDF »

Differential Gene Expression Modulated by the Cytoplasmic Domain of Fc{gamma}RIa (CD64) {alpha}-Chain.

H. Qin, J. C. Edberg, A. W. Gibson, G. P. Page, L. Teng, and R. P. Kimberly (2004)
J. Immunol. 173, 6211-6219
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular Stress Signaling Pathways Activated During Human Islet Preparation and Following Acute Cytokine Exposure.

S. Abdelli, J. Ansite, R. Roduit, T. Borsello, I. Matsumoto, T. Sawada, N. Allaman-Pillet, H. Henry, J. S. Beckmann, B. J. Hering, et al. (2004)
Diabetes 53, 2815-2823
 |  Abstract »  |  Full Text »  |  PDF »

Corticosteroid resistance in rheumatoid arthritis: molecular and cellular perspectives.

I. C. Chikanza and D. L. Kozaci (2004)
Rheumatology 43, 1337-1345
 |  Full Text »  |  PDF »

Overexpression of Phospholipid-hydroperoxide Glutathione Peroxidase in Human Dermal Fibroblasts Abrogates UVA Irradiation-induced Expression of Interstitial Collagenase/Matrix Metalloproteinase-1 by Suppression of Phosphatidylcholine Hydroperoxide-mediated NF{kappa}B Activation and Interleukin-6 Release.

J. Wenk, J. Schuller, C. Hinrichs, T. Syrovets, N. Azoitei, M. Podda, M. Wlaschek, P. Brenneisen, L.-A. Schneider, A. Sabiwalsky, et al. (2004)
J. Biol. Chem. 279, 45634-45642
 |  Abstract »  |  Full Text »  |  PDF »

Expanded Nuclear Roles for I{kappa}Bs.

P. W. Bates and S. Miyamoto (2004)
Sci. STKE 2004, pe48
 |  Abstract »  |  Full Text »  |  PDF »

NF-{kappa}B and AP-1 Connection: Mechanism of NF-{kappa}B-Dependent Regulation of AP-1 Activity.

S. Fujioka, J. Niu, C. Schmidt, G. M. Sclabas, B. Peng, T. Uwagawa, Z. Li, D. B. Evans, J. L. Abbruzzese, and P. J. Chiao (2004)
Mol. Cell. Biol. 24, 7806-7819
 |  Abstract »  |  Full Text »  |  PDF »

{beta}-Arrestin inhibits NF-{kappa}B activity by means of its interaction with the NF-{kappa}B inhibitor I{kappa}B{alpha}.

D. S. Witherow, T. R. Garrison, W. E. Miller, and R. J. Lefkowitz (2004)
PNAS 101, 8603-8607
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular Bacterial Infection-Induced IFN-{gamma} Is Critically but Not Solely Dependent on Toll-Like Receptor 4-Myeloid Differentiation Factor 88-IFN-{alpha}{beta}-STAT1 Signaling.

A. G. Rothfuchs, C. Trumstedt, H. Wigzell, and M. E. Rottenberg (2004)
J. Immunol. 172, 6345-6353
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo Chromatin Remodeling Events Leading to Inflammatory Gene Transcription under Diabetic Conditions.

F. Miao, I. G. Gonzalo, L. Lanting, and R. Natarajan (2004)
J. Biol. Chem. 279, 18091-18097
 |  Abstract »  |  Full Text »  |  PDF »

Identification of an Autoregulatory Feedback Pathway Involving Interleukin-1{alpha} in Induction of Constitutive NF-{kappa}B Activation in Pancreatic Cancer Cells.

J. Niu, Z. Li, B. Peng, and P. J. Chiao (2004)
J. Biol. Chem. 279, 16452-16462
 |  Abstract »  |  Full Text »  |  PDF »

Immunosuppressive Activity of Endovanilloids: N-Arachidonoyl-Dopamine Inhibits Activation of the NF-{kappa}B, NFAT, and Activator Protein 1 Signaling Pathways.

R. Sancho, A. Macho, L. de La Vega, M. A. Calzado, B. L. Fiebich, G. Appendino, and E. Munoz (2004)
J. Immunol. 172, 2341-2351
 |  Abstract »  |  Full Text »  |  PDF »

Hypertonic Stress Activates Glycogen Synthase Kinase 3{beta}-mediated Apoptosis of Renal Medullary Interstitial Cells, Suppressing an NF{kappa}B-driven Cyclooxygenase-2-dependent Survival Pathway.

R. Rao, C.-M. Hao, and M. D. Breyer (2004)
J. Biol. Chem. 279, 3949-3955
 |  Abstract »  |  Full Text »  |  PDF »

Tyrosine Kinase p56lck Regulates Cell Motility and Nuclear Factor {kappa}B-mediated Secretion of Urokinase Type Plasminogen Activator through Tyrosine Phosphorylation of I{kappa}B{alpha} following Hypoxia/Reoxygenation.

G. H. Mahabeleshwar and G. C. Kundu (2003)
J. Biol. Chem. 278, 52598-52612
 |  Abstract »  |  Full Text »  |  PDF »

Hepatitis C Virus NS5A and Subgenomic Replicon Activate NF-{kappa}B via Tyrosine Phosphorylation of I{kappa}B{alpha} and Its Degradation by Calpain Protease.

G. Waris, A. Livolsi, V. Imbert, J.-F. Peyron, and A. Siddiqui (2003)
J. Biol. Chem. 278, 40778-40787
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NF{kappa}B Regulates Plasma Apolipoprotein A-I and High Density Lipoprotein Cholesterol through Inhibition of Peroxisome Proliferator-activated Receptor {alpha}.

A. Morishima, N. Ohkubo, N. Maeda, T. Miki, and N. Mitsuda (2003)
J. Biol. Chem. 278, 38188-38193
 |  Abstract »  |  Full Text »  |  PDF »

Hepatitis C Virus and HIV Envelope Proteins Collaboratively Mediate Interleukin-8 Secretion through Activation of p38 MAP Kinase and SHP2 in Hepatocytes.

A. Balasubramanian, R. K. Ganju, and J. E. Groopman (2003)
J. Biol. Chem. 278, 35755-35766
 |  Abstract »  |  Full Text »  |  PDF »

Recombinant TCR Ligand Induces Early TCR Signaling and a Unique Pattern of Downstream Activation.

C. Wang, J. L. Mooney, R. Meza-Romero, Y. K. Chou, J. Huan, A. A. Vandenbark, H. Offner, and G. G. Burrows (2003)
J. Immunol. 171, 1934-1940
 |  Abstract »  |  Full Text »  |  PDF »

NF-{kappa}B Inhibits Gammaherpesvirus Lytic Replication.

H. J. Brown, M. J. Song, H. Deng, T.-T. Wu, G. Cheng, and R. Sun (2003)
J. Virol. 77, 8532-8540
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Factor-{kappa}B Mediates Angiogenesis and Metastasis of Human Bladder Cancer through the Regulation of Interleukin-8.

T. Karashima, P. Sweeney, A. Kamat, S. Huang, S. J. Kim, M. Bar-Eli, D. J. McConkey, and C. P. N. Dinney (2003)
Clin. Cancer Res. 9, 2786-2797
 |  Abstract »  |  Full Text »  |  PDF »

Yin Yang 1 Is a Lipopolysaccharide-Inducible Activator of the Murine 3' Igh Enhancer, hs3.

S. J. Gordon, S. Saleque, and B. K. Birshtein (2003)
J. Immunol. 170, 5549-5557
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo Identification of Inducible Phosphoacceptors in the IKK{gamma}/NEMO Subunit of Human I{kappa}B Kinase.

R. S. Carter, K. N. Pennington, B. J. Ungurait, and D. W. Ballard (2003)
J. Biol. Chem. 278, 19642-19648
 |  Abstract »  |  Full Text »  |  PDF »

Two Distinct Phases of Virus-induced Nuclear Factor kappa B Regulation Enhance Tumor Necrosis Factor-related Apoptosis-inducing Ligand-mediated Apoptosis in Virus-infected Cells.

P. Clarke, S. M. Meintzer, L. A. Moffitt, and K. L. Tyler (2003)
J. Biol. Chem. 278, 18092-18100
 |  Abstract »  |  Full Text »  |  PDF »

Diminished Heme Oxygenase Potentiates Cell Death: Pyrrolidinedithiocarbamate Mediates Oxidative Stress.

L. Malaguarnera, S. Quan, M. R. Pilastro, N. G. Abraham, and A. Kappas (2003)
Experimental Biology and Medicine 228, 459-465
 |  Abstract »  |  Full Text »  |  PDF »

Aspirin inhibits Chlamydia pneumoniae-induced NF-{kappa}B activation, cyclo-oxygenase-2 expression and prostaglandin E2 synthesis and attenuates chlamydial growth.

H. Yoneda, K. Miura, H. Matsushima, K. Sugi, T. Murakami, K. Ouchi, K. Yamashita, H. Itoh, T. Nakazawa, M. Suzuki, et al. (2003)
J. Med. Microbiol. 52, 409-415
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of protein tyrosine kinase in Toll-like receptor 4-mediated NF-kappa B activation in human peripheral blood monocytes.

L.-Y. Chen, B. L. Zuraw, M. Zhao, F.-T. Liu, S. Huang, and Z. K. Pan (2003)
Am J Physiol Lung Cell Mol Physiol 284, L607-L613
 |  Abstract »  |  Full Text »  |  PDF »

Microtubule Disruption Utilizes an NFkappa B-dependent Pathway to Stabilize HIF-1alpha Protein.

Y.-J. Jung, J. S. Isaacs, S. Lee, J. Trepel, and L. Neckers (2003)
J. Biol. Chem. 278, 7445-7452
 |  Abstract »  |  Full Text »  |  PDF »

Down-regulation of Hydrogen Peroxide-induced PKCdelta Activation in N-Acetylglucosaminyltransferase III-transfected HeLaS3 Cells.

Y. Shibukawa, M. Takahashi, I. Laffont, K. Honke, and N. Taniguchi (2003)
J. Biol. Chem. 278, 3197-3203
 |  Abstract »  |  Full Text »  |  PDF »

p105{middle dot}Ikappa Bgamma and Prototypical Ikappa Bs Use a Similar Mechanism to Bind but a Different Mechanism to Regulate the Subcellular Localization of NF-kappa B.

A. K. Moorthy and G. Ghosh (2003)
J. Biol. Chem. 278, 556-566
 |  Abstract »  |  Full Text »  |  PDF »

NF-kappa B inhibition by omega -3 fatty acids modulates LPS-stimulated macrophage TNF-alpha transcription.

T. E. Novak, T. A. Babcock, D. H. Jho, W. S. Helton, and N. J. Espat (2003)
Am J Physiol Lung Cell Mol Physiol 284, L84-L89
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Nuclear Factor-{kappa}B by Corticotropin-Releasing Hormone in Mouse Thymocytes.

J. Zhao and K. P. Karalis (2002)
Mol. Endocrinol. 16, 2561-2570
 |  Abstract »  |  Full Text »  |  PDF »

IKKbeta Is Required for Bcl-2-mediated NF-kappa B Activation in Ventricular Myocytes.

K. M. Regula, K. Ens, and L. A. Kirshenbaum (2002)
J. Biol. Chem. 277, 38676-38682
 |  Abstract »  |  Full Text »  |  PDF »

Fc{gamma}R cross-linking mediates NF-{kappa}B activation, reduced antigen presentation capacity, and decreased IL-12 production in monocytes without modulation of myeloid dendritic cell development.

Y. Drechsler, S. Chavan, D. Catalano, P. Mandrekar, and G. Szabo (2002)
J. Leukoc. Biol. 72, 657-667
 |  Abstract »  |  Full Text »  |  PDF »

Low Intracellular Zinc Impairs the Translocation of Activated NF-kappa B to the Nuclei in Human Neuroblastoma IMR-32 Cells.

G. G. Mackenzie, M. P. Zago, C. L. Keen, and P. I. Oteiza (2002)
J. Biol. Chem. 277, 34610-34617
 |  Abstract »  |  Full Text »  |  PDF »

Heat Shock Protein 70 Is a Potential Virulence Factor in Murine Toxoplasma Infection Via Immunomodulation of Host NF-{kappa}B and Nitric Oxide.

C. A. Dobbin, N. C. Smith, and A. M. Johnson (2002)
J. Immunol. 169, 958-965
 |  Abstract »  |  Full Text »  |  PDF »

Carnosol, an antioxidant in rosemary, suppresses inducible nitric oxide synthase through down-regulating nuclear factor-{kappa}B in mouse macrophages.

A.-H. Lo, Y.-C. Liang, S.-Y. Lin-Shiau, C.-T. Ho, and J.-K. Lin (2002)
Carcinogenesis 23, 983-991
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Factor Kappa B Activation and Regulation of Cyclooxygenase Type-2 Expression in Human Amnion Mesenchymal Cells by Interleukin-1{beta}.

X. Yan, C. Wu Xiao, M. Sun, B. K. Tsang, and W. Gibb (2002)
Biol Reprod 66, 1667-1671
 |  Abstract »  |  Full Text »  |  PDF »

Heme Oxygenase-1-derived Carbon Monoxide Requires the Activation of Transcription Factor NF-kappa B to Protect Endothelial Cells from Tumor Necrosis Factor-alpha -mediated Apoptosis.

S. Brouard, P. O. Berberat, E. Tobiasch, M. P. Seldon, F. H. Bach, and M. P. Soares (2002)
J. Biol. Chem. 277, 17950-17961
 |  Abstract »  |  Full Text »  |  PDF »

DNA Binding-Independent Induction of I{kappa}B{alpha} Gene Transcription by PPAR{alpha}.

P. Delerive, K. De Bosscher, W. Vanden Berghe, J.-C. Fruchart, G. Haegeman, and B. Staels (2002)
Mol. Endocrinol. 16, 1029-1039
 |  Abstract »  |  Full Text »  |  PDF »

Contrasting the Roles of Costimulation and the Natural Adjuvant Lipopolysaccharide During the Induction of T Cell Immunity.

J. R. Maxwell, C. Ruby, N. I. Kerkvliet, and A. T. Vella (2002)
J. Immunol. 168, 4372-4381
 |  Abstract »  |  Full Text »  |  PDF »

MDM2 induces NF-kappa B/p65 expression transcriptionally through Sp1-binding sites: a novel, p53-independent role of MDM2 in doxorubicin resistance in acute lymphoblastic leukemia.

L. Gu, H. W. Findley, and M. Zhou (2002)
Blood 99, 3367-3375
 |  Abstract »  |  Full Text »  |  PDF »

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