Science, Vol 242, Issue 4880, 885-892
Copyright © 1988 by American Association for the Advancement of Science
Biomaterials and biomedical devices
JS Hanker
and
BL Giammara
Biomedical Engineering Curriculum, University of North Carolina, Chapel Hill 27599.
This review discusses the factors important in the incorporation or integration of biomaterials and devices by tissue. Methods for surface modification and surface-sensitive techniques for analysis are cited. In vitro methods to evaluate the biocompatibility or efficacy of certain biomaterials and devices are presented. Present and future directions in neural prostheses, cardiovascular materials, blood or bone substitutes, controlled drug delivery, orthopedic prostheses, dental materials, artificial organs, plasma- and cytapheresis, and dialysis are discussed.