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Science 28 November 2008:
Vol. 322. no. 5906, pp. 1337 - 1338
DOI: 10.1126/science.1167452
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Perspectives

MICROBIOLOGY:
An Antibiotic Mimics Immunity

Carl Nathan

Certain compounds generate reactive nitrogen intermediates in bacteria, contributing to their antimicrobial effect.

The Department of Microbiology and Immunology, Weill Cornell Medical College, New York, NY 10065, USA. E-mail: cnathan{at}med.cornell.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Conversion of NO2 to NO by reduced coenzyme F420 protects mycobacteria from nitrosative damage.
E. Purwantini and B. Mukhopadhyay (2009)
PNAS 106, 6333-6338
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Science. ISSN 0036-8075 (print), 1095-9203 (online)