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Science 14 November 2008:
Vol. 322. no. 5904, p. 1039
DOI: 10.1126/science.322.5904.1039
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News of the Week

CARDIOVASCULAR HEALTH:
Statin Therapy Reduces Disease in Healthy Volunteers--But How, Exactly?

Jennifer Couzin

Some experts are calling the 17,800-person JUPITER trial a huge success in preventing cardiovascular disease and proving the value of c-reactive protein, an indicator of inflammation, as a risk marker for heart disease. The trial comes with a host of caveats, however, muddying the picture of inflammation’s role in cardiovascular disease.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)